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HRID1804389

反应详情

EQUATION

反应方程式

HRID 1804389 的结构方程式

REACTANTS

反应物

2
结构：O=C1N=CCO1
HCID14405094

1,3-Oxazol-2(5H)-one

C3H3NO2

结构：O=C(c1ccc(Br)cc1F)N1CCN(c2ccc(C3CC3)cn2)CC1
HCID58484657

未命名化合物

PRODUCTS

生成物

1
结构：O=C(c1ccc(N2CCOC2=O)cc1F)N1CCN(c2ccc(C3CC3)cn2)CC1
HCID58484820

未命名化合物

收率 74.4%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 110 and using (4-bromo-2-fluorophenyl)[4-(5-cyclopropylpyridin-2-yl)piperazin-1-yl]methanone (404 mg) described in Preparation Example 188 and oxazolin-2-one (104 mg), the title compound (305 mg) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner as in Example 110