HRID1804394

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14405094

1,3-Oxazol-2(5H)-one

C3H3NO2

结构：Cc1cnc(N2CCN(C(=O)c3ccc(Br)cc3C#N)CC2)c(C)c1

HCID58484628

未命名化合物

PRODUCTS

生成物

结构：Cc1cnc(N2CCN(C(=O)c3ccc(N4CCOC4=O)cc3C#N)CC2)c(C)c1

HCID58484493

未命名化合物

收率 80.7%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Example 110 and using 5-bromo-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]benzonitrile (399 mg) described in Preparation Example 193 and oxazolin-2-one (104 mg), the title compound (327 mg) was obtained.

WORKUP

后处理

customBy reaction and treatment in the same manner as in Example 110