1,3-Oxazol-2(5H)-one → 3-{3-Cyano-4-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}oxazolidin-2-one

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1,3-Oxazol-2(5H)-one	HCID 14405094	—
Edukt	5-Bromo-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]benzonitrile	HCID 58484628	—
Produkt	3-{3-Cyano-4-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}oxazolidin-2-one	HCID 58484493	80,7%

Reaktionsschritte

By reaction and treatment in the same manner as in Example 110 and using 5-bromo-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]benzonitrile (399 mg) described in Preparation Example 193 and oxazolin-2-one (104 mg), the title compound (327 mg) was obtained.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08354401B2
Quelldatensatz	uspto-grants-2013_01
ORD ID	ord-d8173770f7624ce192e0329bc3d624da
Quellennotiz	uspto-grants-2013_01