huagongshe.com
HRID1804405

反应详情

EQUATION

反应方程式

HRID 1804405 的结构方程式

REACTANTS

反应物

2
结构：Cc1cc(Br)cnc1N1CCNCC1
HCID46739270

1-(5-Bromo-3-methylpyridin-2-yl)piperazine

C10H14BrN3

结构：C[C@@H]1COC(=O)N1c1ccc(C(=O)O)cc1
HCID58484719

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(Br)cnc1N1CCN(C(=O)c2ccc(N3C(=O)OC[C@H]3C)cc2)CC1
HCID67381057

未命名化合物

收率 96.7%

PROCEDURE

实验过程

By reaction and treatment in the same manner as in Preparation Example 67 and using (R)-4-(4-methyl-2-oxooxazolidin-3-yl)benzoic acid (1.3 g) described in Preparation Example 37 and 1-(5-bromo-3-methylpyridin-2-yl)piperazine (1.5 g), (R)-3-{4-[4-(5-bromo-3-methylpyridin-2-yl)piperazine-1-carbonyl]phenyl}-4-methyloxazolidin-2-one (2.6 g) was obtained.

WORKUP

后处理

  1. customBy reaction and treatment in the same manner
  2. customas in Preparation Example 67