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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804405Generated: October 31, 2026

1-(5-Bromo-3-methylpyridin-2-yl)piperazine → HCID 67381057, compound

https://huagongshe.com/reaction/1804405

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(5-Bromo-3-methylpyridin-2-yl)piperazineHCID 46739270—
Reactant(R)-4-(4-methyl-2-oxooxazolidin-3-yl)benzoic acidHCID 58484719—
ProductHCID 67381057HCID 6738105796.7%

Reaction Steps

By reaction and treatment in the same manner as in Preparation Example 67 and using (R)-4-(4-methyl-2-oxooxazolidin-3-yl)benzoic acid (1.3 g) described in Preparation Example 37 and 1-(5-bromo-3-methylpyridin-2-yl)piperazine (1.5 g), (R)-3-{4-[4-(5-bromo-3-methylpyridin-2-yl)piperazine-1-carbonyl]phenyl}-4-methyloxazolidin-2-one (2.6 g) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354401B2
Source datasetuspto-grants-2013_01
ORD IDord-0909fced3eac4966b22fc3c8628475b6
Source noteuspto-grants-2013_01