Acetone → Hydrochloric Acid

HRID 180452Notes

Reaction equation

HRID 180452 reaction equation
[CH2:1]([CH2:2][CH3:3])[N:4]1[CH:5]([CH2:9][NH:10][C:11]([c:12]2[c:13]([O:21][CH3:22])[c:14]([Br:20])[cH:15][cH:16][c:17]2[O:18][CH3:19])=[O:23])[CH2:6][CH2:7][CH2:8]1.[CH3:25][C:26](=[O:27])[CH3:28].[CH3:29][CH2:30][OH:31].[ClH:24]>>[CH2:1]([CH2:2][CH3:3])[N:4]1[CH:5]([CH2:9][NH:10][C:11]([c:12]2[c:13]([OH:21])[c:14]([Br:20])[cH:15][cH:16][c:17]2[O:18][CH3:19])=[O:23])[CH2:6][CH2:7][CH2:8]1.[ClH:24]

Participants

6

Reactant 4

HCID 180AcetoneHCID 313Hydrochloric AcidHCID 702EthanolHCID 13493825(-)-N-n-propyl-2-(3-bromo-2,6-dimethoxybenzamidomethyl)pyrrolidine

Product 2

HCID 313Hydrochloric AcidHCID 134938273-bromo-2-hydroxy-6-methoxy-N-[(1-propylpyrrolidin-2-yl)methyl]benzamide

Sources & evidence

ORD record
ord-56c863c5016e4cc59211ae26e2f2b869
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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