Hydrochloric Acid → 943845-80-5

HRID 1804545노트

반응식

HRID 1804545 반응식
[O:1]=[C:2]1[CH2:6][CH2:5][CH2:4][N:3]1[C:7]1[CH:8]=[C:9]([CH:19]=[CH:20][CH:21]=1)[CH2:10][NH:11]C(=O)OC(C)(C)C.[ClH:22]>ClCCl>[ClH:22].[NH2:11][CH2:10][C:9]1[CH:8]=[C:7]([N:3]2[CH2:4][CH2:5][CH2:6][C:2]2=[O:1])[CH:21]=[CH:20][CH:19]=1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 59462263HCID 59462263, 화합물

생성물 1

HCID 68967881943845-80-5

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

500 mg (1.72 mmol) tert-butyl [3-(2-oxo-pyrrolidin-1-yl)-benzyl]-carbamate are placed in 2 ml dichloromethane, 4.00 ml (8 mmol) 2 molar ethereal hydrochloric acid are added. The mixture is stirred for 16 hours at ambient temperature, then evaporated down. The residue is crystallised with acetone/ethanol and diethyl ether.

후처리

  1. customevaporated down
  2. customThe residue is crystallised with acetone/ethanol and diethyl ether

출처 및 근거

ORD 기록
ord-963ee1c8b2534ca992ff1e26e0228793
출처 데이터셋
uspto-grants-2013_01
특허 번호
US08354418B2

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