Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804555Generated: November 1, 2026

Benzyl [2-(5-ethyloxazol-2-yl)ethyl]carbamate → 2-(5-Ethyloxazol-2-yl)ethylamine

https://huagongshe.com/reaction/1804555

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl [2-(5-ethyloxazol-2-yl)ethyl]carbamateHCID 57636953—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product2-(5-Ethyloxazol-2-yl)ethylamineHCID 11542801—

Reaction Steps

2.86 g (10.43 mmol) benzyl [2-(5-ethyl-oxazol-2-yl)-ethyl]-carbamate are placed in 130 ml of methanol, 0.910 mg palladium/charcoal 10% are added, then the mixture is hydrogenated for 5 hours at ambient temperature under a pressure of 14 psi. Then the catalyst is suction filtered and the solution is evaporated down.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354418B2
Source datasetuspto-grants-2013_01
ORD IDord-0bb8f8b4496347e4a8a9fb4994d8c8a2
Source noteuspto-grants-2013_01