Hydrochloric Acid → [2-(3-Ethyl-1,2,4-oxadiazol-5-yl)ethyl]amine hydrochloride

Participants

Reaction Conditions

Reaction Steps

2.05 g (8.50 mmol) tert-butyl [2-(3-ethyl-[1,2,4]oxadiazol-5-yl)-ethyl]-carbamate are placed in 20 ml dichloromethane and 40 ml of 1 molar ethereal hydrochloric acid are added. The reaction mixture is stirred for 16 hours at ambient temperature and 4 hours at 40° C. After the addition of a further 10 ml ethereal hydrochloric acid stirring is continued for 72 hours at ambient temperature. The suspension is evaporated down.

Provenance & Evidence