HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 4-(1,3-thiazol-4-yl)piperidine-1-carboxylate → 4-(1,3-Thiazol-4-yl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 4-(1,3-thiazol-4-yl)piperidine-1-carboxylate | HCID 53485228 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 4-(1,3-Thiazol-4-yl)piperidine | HCID 39236249 | 94% |
Reaction Steps
The title compound from Step C above (280 mg, 1.04 mmol) was dissolved in 4 M HCl in dioxane (4.0 mL) and stirred at RT for 1 h. The product was concentrated under reduced pressure and dried under high vacuum to give the title compound (i-30) (237 mg, 94%). ESI-MS calculated for C8H12N2S: Exact Mass: 168.07. Found 169.07.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354403B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-bf3b05b113874f4195859adc25366651 |
| Source note | uspto-grants-2013_01 |