HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-pyrrolo(2,3-b)pyridin-5-amine → HCID 44194001, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-pyrrolo(2,3-b)pyridin-5-amine | HCID 11715187 | — |
| Reactant | 5-fluoro-1-(3-fluorobenzyl)-1H-indole-2-carboxylic acid | HCID 57431513 | — |
| Product | HCID 44194001 | HCID 44194001 | 78.7% |
Reaction Steps
The process is performed according to a method similar to that described in Example 1.3 starting with 0.4 g (1.39 mmol) of 5-fluoro-1-(3-fluorobenzyl)-1H-indole-2-carboxylic acid prepared in step 1.1 and 0.22 g (1.67 mmol) of 5-amino-1H-pyrrolo[2,3-b]pyridine (Synthesis 2005, 15, 2503). 0.44 g of the expected product is thus isolated in the form of a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354425B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-4e23bac06cd6413faed62fd2231c42d1 |
| Source note | uspto-grants-2013_01 |