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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1804738Generated: November 2, 2026

1H-pyrrolo(2,3-b)pyridin-5-amine → HCID 44194001, compound

https://huagongshe.com/reaction/1804738

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-pyrrolo(2,3-b)pyridin-5-amineHCID 11715187—
Reactant5-fluoro-1-(3-fluorobenzyl)-1H-indole-2-carboxylic acidHCID 57431513—
ProductHCID 44194001HCID 4419400178.7%

Reaction Steps

The process is performed according to a method similar to that described in Example 1.3 starting with 0.4 g (1.39 mmol) of 5-fluoro-1-(3-fluorobenzyl)-1H-indole-2-carboxylic acid prepared in step 1.1 and 0.22 g (1.67 mmol) of 5-amino-1H-pyrrolo[2,3-b]pyridine (Synthesis 2005, 15, 2503). 0.44 g of the expected product is thus isolated in the form of a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354425B2
Source datasetuspto-grants-2013_01
ORD IDord-4e23bac06cd6413faed62fd2231c42d1
Source noteuspto-grants-2013_01