HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Pyrrolo[3,2-b]pyridin-6-amine → HCID 44194003, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Pyrrolo[3,2-b]pyridin-6-amine | HCID 24229268 | — |
| Reactant | 5-fluoro-1-(3-fluorobenzyl)-1H-indole-2-carboxylic acid | HCID 57431513 | — |
| Product | HCID 44194003 | HCID 44194003 | 39.3% |
Reaction Steps
The process is performed according to a method similar to that of Example 1.3 starting with 0.4 g (1.39 mmol) of 5-fluoro-1-(3-fluorobenzyl)-1H-indole-2-carboxylic acid prepared in step 1.1 and 0.22 g (1.67 mmol) of 6-amino-1H-pyrrolo[3,2-b]pyridine (Adesis). 0.22 g of the expected product is thus isolated in the form of a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354425B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-2051a697c9c043c181a02c024548a03e |
| Source note | uspto-grants-2013_01 |