反应详情

Compound 30 was prepared according to a process similar to that described in step 5.1 by reacting 186 mg (0.523 mmol) of ethyl 5-trifluoromethyl-1-[(thiazol-2-yl)methyl]-1H-pyrrolo[2,3-b]pyridine-2-carboxylate prepared according to the protocol described in step 7.1 with 84 mg (0.628 mmol) of pyrrolo[2,3-b]pyrid-5-ylamine in the presence of 0.39 mL (0.785 mmol) of a solution of trimethylaluminium (2M/toluene). The product is collected by filtration, to give 144 mg of expected product.

1. customCompound 30 was prepared
2. customprepared
3. filtrationThe product is collected by filtration