2-(6-Methoxy-1-benzofuran-3-yl)acetic acid → 2-(6-Methoxy-benzofuran-3-yl)ethanol

Participants

Reaction Steps

A solution of (6-methoxy-benzofuran-3-yl)-acetic acid (10.16 g, 49.3 mmol) in 500 ml of THF is cooled in an ice-bath. To this solution is added LAH (1M in THF, 49.3 ml, 49.3 mmol) and stirring is continued for 1 hour. The reaction mixture is then poured onto ice cold 1N HCl and extracted 3-times with EtOAc. The combined organic layers are dried and evaporated.

Provenance & Evidence