反应详情

A solution of (6-methoxy-benzofuran-3-yl)-acetic acid (10.16 g, 49.3 mmol) in 500 ml of THF is cooled in an ice-bath. To this solution is added LAH (1M in THF, 49.3 ml, 49.3 mmol) and stirring is continued for 1 hour. The reaction mixture is then poured onto ice cold 1N HCl and extracted 3-times with EtOAc. The combined organic layers are dried and evaporated.

1. additionThe reaction mixture is then poured onto ice cold 1N HCl
2. extractionextracted 3-times with EtOAc
3. customThe combined organic layers are dried
4. customevaporated