Toluene → Ethyl 4,4-difluoro-3-oxo-2-(piperidin-1-ylmethylidene)butyrate
Reaction equation
[CH3:20][CH2:21][CH2:22][CH2:23][N:24]([CH2:25][CH2:26][CH2:27][CH3:28])[CH2:29][CH2:30][CH2:31][CH3:32].[CH3:33][c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1.[F:14][CH:15]([C:16](=[O:17])[F:18])[F:19].[N:1]1([CH:7]=[CH:8][C:9](=[O:10])[O:11][CH2:12][CH3:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1>>[N:1]1([CH:7]=[C:8]([C:9](=[O:10])[O:11][CH2:12][CH3:13])[C:16]([CH:15]([F:14])[F:19])=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
5
Sources & evidence
- ORD record
- ord-b19736fff5f24dd4b89f88cd27010f6a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…