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HRID1806499

反应详情

EQUATION

反应方程式

HRID 1806499 的结构方程式

REACTANTS

反应物

2
结构：CNCc1c(C)n[nH]c1C
HCID28305800

未命名化合物

结构：CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4csc(CN(C)Cc5c(C)n[nH]c5C)c4)cc23)CC1
HCID57732723

未命名化合物

PRODUCTS

生成物

1
结构：CCS(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4csc(CN(C)CC#N)c4)cc23)CC1
HCID57732681

未命名化合物

收率 12.7%

PROCEDURE

实验过程

The title compound was prepared according to the general procedure of 5-(5-{[[(3,5-dimethyl-1H-pyrazol-4-yl)methyl](methyl)amino]methyl}-3-thienyl)-3-[1-(ethylsulfonyl)-4-piperidinyl]-1H-indole-7-carboxamide, substituting (methylamino)acetonitrile (320 μmol) for 1-(3,5-dimethyl-1H-pyrazol-4-yl)-N-methylmethanamine to afford 6.36 mg of the title compound (12.7%).

WORKUP

后处理

  1. customThe title compound was prepared