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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 180683Generated: October 25, 2026

Citric Acid → ethyl 2-(4-iodo-1H-pyrazolo[3,4-b]pyridin-1-yl)-3-(tetrahydro-2H-pyran-4-yl)propanoate

https://huagongshe.com/reaction/180683

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCitric AcidHCID 311—
ReactantPotassium CationHCID 813—
ReactantDimethylformamideHCID 6228—
ReactantCarbonate IonHCID 19660—
Reactantethyl 3-(tetrahydro-2H-pyran-4-yl)-2-propenoateHCID 54040092—
Reactant4-Iodo-1H-pyrazolo[3,4-b]pyridineHCID 57642801—
Reactantethyl 2-bromo-3-(tetrahydro-2H-pyran-4-yl)propanoateHCID 58380608—
Productethyl 2-(4-iodo-1H-pyrazolo[3,4-b]pyridin-1-yl)-3-(tetrahydro-2H-pyran-4-yl)propanoateHCID 58380598—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-c892e527c36646abbfb0571855162fd8
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)