Citric Acid → ethyl 2-(4-iodo-1H-pyrazolo[3,4-b]pyridin-1-yl)-3-(tetrahydro-2H-pyran-4-yl)propanoate
Reaction equation
[Br:11][CH:12]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[CH2:18][CH:19]1[CH2:20][CH2:21][O:22][CH2:23][CH2:24]1.[C:38](=[O:39])([O-:40])[O-:41].[CH3:57][N:58]([CH3:59])[CH:60]=[O:61].[I:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[nH:8][n:9][cH:10]2.[K+:42].[K+:43].[O:25]1[CH2:26][CH2:27][CH:28]([CH:29]=[CH:30][C:31]([O:32][CH2:33][CH3:34])=[O:35])[CH2:36][CH2:37]1.[OH:44][C:45]([CH2:46][C:47]([C:48](=[O:49])[OH:50])([CH2:51][C:52](=[O:53])[OH:54])[OH:55])=[O:56]>>[I:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[n:8]([CH:12]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[CH2:18][CH:19]1[CH2:20][CH2:21][O:22][CH2:23][CH2:24]1)[n:9][cH:10]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-c892e527c36646abbfb0571855162fd8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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