HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycine tert-butyl ester → HCID 178451249, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycine tert-butyl ester | HCID 151417 | — |
| Reactant | 2-(Oxan-4-yl)acetaldehyde | HCID 17750943 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178451249 | HCID 178451249 | 35.6% |
Reaction Steps
In a manner similar to the method described in Example 1a, glycine tert-butyl ester (0.65 g, 5 mmol) was reacted with (tetrahydro-pyran-4-yl)-acetaldehyde (Pharmacore) (0.64 g, 5 mmol) in CH2Cl2 at room temperature for 5 h to give [2-(tetrahydro-pyran-4-yl)-eth-(E)-ylideneamino]-acetic acid tert-butyl ester as a colorless oil (0.43 g, 33%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08354444B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-bd884d940e4b4e6cb0779ba333429a50 |
| Source note | uspto-grants-2013_01 |