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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1806918Generated: November 3, 2026

Glycine tert-butyl ester → HCID 178451254, compound

https://huagongshe.com/reaction/1806918

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycine tert-butyl esterHCID 151417—
Reactant2,2-Dimethyl-4-oxo-butyric acid benzyl esterHCID 85656846—
SolventDichloromethaneHCID 6344—
ProductHCID 178451254HCID 17845125493.2%

Reaction Steps

Step D In a manner similar to the method described in Example 1a, glycine tert-butyl ester (1.72 g, 13.2 mmol) was reacted with 2,2-dimethyl-4-oxo-butyric acid benzyl ester (4.1 g, 132 mmol) in CH2Cl2 at room temperature for 18 h to give 4-[(E)-tert-butoxycarbonylmethylimino]-2,2-dimethyl-butyric acid benzyl ester as a colorless oil (4.1 g, 93%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08354444B2
Source datasetuspto-grants-2013_01
ORD IDord-8bcdc774b7c84b5cad02a21b0e7eed80
Source noteuspto-grants-2013_01