Ethanolamine → HCID 49800449, compound

Participants

Reaction Steps

As described for example 9, 6-(3-butyl-5-methyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester (500 mg, 1.4 mmol) was converted, using ethanolamine instead of rac-2-amino-1-propanol, to the title compound (280 mg, 60%) which was obtained as a colourless oil after purification by chromatography (silica, 0 to 5% methanol in dichloromethane). MS: m/e=334.3 [M+H]+.

Provenance & Evidence