HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorotrimethylsilane → HCID 68787557, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorotrimethylsilane | HCID 6397 | — |
| Reactant | HCID 44241901 | HCID 44241901 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | HCID 68787557 | HCID 68787557 | — |
Reaction Steps
Me3SiCl (0.3 ml, 2.4 mmol) was added to a solution of (S)-2-(4-(dimethylamino)-4-phenylcyclohexylamino)-3-(1H-indol-3-yl)-N,N-dimethylpropanamide (420 mg, 0.9 mmol, polar diastereomer from step 3) in ethyl methyl ketone (10 ml). The solid was aspirated after a reaction time of 1 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08357705B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-6991bdc971cb47aa817affbb62c6772c |
| Source note | uspto-grants-2013_01 |