Trifluoroacetic acid methylene chloride → HCID 66691915, compound

Participants

Reaction Steps

tert-butyl 4-(6-amino-3,5-dichloropyridin-2-yl)piperazine-1-carboxylate (110 mg, 0.305 mmol,) was treated with 50% TFA/DCM for 1 h, then drained and dried in vacuum to give 3,5-dichloro-6-(piperazin-1-yl)pyridin-2-amine (110 mg, 0.305 mmol). 1H-NMR (CD3OD-d4, 500 MHz): δ7.51 (1H, s), 3.51 (4H, m), 3.31 (4H, m).

Provenance & Evidence