Hydrochloric Acid → 5,6-dimethyl-1-[5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepane hydrochloride

Participants

Reaction Steps

Hydrogen chloride gas was bubbled through a 0° C. solution of the compound 1-6 (385 mg, 0.93 mmol) in ethyl acetate (5 mL) for 1 minute. The reaction was sealed and stirred for 40 minutes. Concentration in vacuo gave the titled compound as a white solid. Data for 1-7: LC/MS: m/z (M+Na)=314.2 found; 314.4 calculated.

Provenance & Evidence