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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 18095Generated: October 29, 2026

Trifluoroacetic acid → HCID 67089785, compound

https://huagongshe.com/reaction/18095

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant(Pyrido[2,3-b]pyrazin-2-ylaminomethyl)-piperidine-1-carboxylic acid tert butyl esterHCID 69284289—
SolventDichloromethaneHCID 6344—
ProductHCID 67089785HCID 67089785—

Reaction Steps

2-(Pyrido[2,3-b]pyrazin-2-ylaminomethyl)-piperidine-1-carboxylic acid tert butyl ester (0.48 g) was dissolved in dichloromethane (3 ml), cooled (ice bath) and treated with trifluoroacetic acid (2 ml). The mixture was stirred for 3 hours at room temperature, solvent removed at reduced pressure and the residue co-evaporated with toluene to give the title compound (0.45 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07741329B2
Source datasetuspto-grants-2010_06
ORD IDord-fc60f30ac7954d81b9a4604df3ee0f47
Source noteuspto-grants-2010_06