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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1809522Generated: October 30, 2026

Methyl 3-cyano-4-(cyclopropylmethoxy)benzoate → 3-Cyano-4-(cyclopropylmethoxy)benzoic acid

https://huagongshe.com/reaction/1809522

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-cyano-4-(cyclopropylmethoxy)benzoateHCID 66877477—
Reactant3-Cyano-5-isopropoxybenzoic acidHCID 67196214—
Product3-Cyano-4-(cyclopropylmethoxy)benzoic acidHCID 66878001—

Reaction Steps

Prepared from methyl 3-cyano-4-(cyclopropylmethoxy)benzoate according to the procedure for 3-cyano-5-isopropoxybenzoic acid. LCMS-ESI (m/z) calculated for C12H11NO3; 217.2; no ink observed, tR=2.92 min. 1H NMR (400 MHz, CDCl3) δ 8.24-8.08 (m, 2H), 7.32 (d, J=8.9 Hz, 1H), 4.09 (d, J=7.1 Hz, 2H), 1.28 (s, 1H), 0.71-0.52 (m, 2H), 0.49-0.31 (m, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08362048B2
Source datasetuspto-grants-2013_01
ORD IDord-28480cd2677046dda98965e0328858b7
Source noteuspto-grants-2013_01