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HRID18097

反应详情

EQUATION

反应方程式

HRID 18097 的结构方程式

REACTANTS

反应物

3
结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：CC(C)(C)OC(=O)N1CCCC[C@H]1CN
HCID1502020

tert-Butyl (2S)-2-(aminomethyl)piperidine-1-carboxylate

C11H22N2O2

结构：N#Cc1ccc(Cl)nc1
HCID5152094

2-Chloro-5-cyanopyridine

C6H3ClN2

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCCCC1CNc1ccc(C#N)cn1
HCID86593677

未命名化合物

收率 52.3%

PROCEDURE

实验过程

The title compound (1.54 g) was prepared from (S)-2-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester (2.0 g) and 2-chloro-5-cyanopyridine (1.29 g) in the presence of diisopropylethylamine (1.21 g) according to the method of D28.