HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(3-Fluoro-5-nitrophenoxy)pyridine → 3-Fluoro-5-(pyridin-3-yloxy)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(3-Fluoro-5-nitrophenoxy)pyridine | HCID 57353642 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-Fluoro-5-(pyridin-3-yloxy)aniline | HCID 53439638 | — |
Reaction Steps
A palladium-carbon catalyst was added to a solution of 3-(3-fluoro-5-nitrophenoxy)pyridine (8.0 g) in methanol (70 ml), and the reaction solution was stirred under hydrogen atmosphere at room temperature for 2 hours. The reaction solution was filtered through Celite, and the filtrate was distilled off under reduced pressure to obtain a crude product as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08362052B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-dd0f6cd2abb04f5ea8b478628379aadf |
| Source note | uspto-grants-2013_01 |