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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1810060Generated: November 1, 2026

3-Butyn-1-OL → HCID 178449564, compound

https://huagongshe.com/reaction/1810060

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Butyn-1-OLHCID 13566—
Reactant(2-Aminothiazole-5-ylsulfanyl)-propionic acid ethyl esterHCID 86610213—
ReactantHCID 178460760HCID 178460760—
ProductHCID 178449564HCID 178449564—

Reaction Steps

The compound was prepared following an analogous procedure to the one described for the synthesis of 2-methyl-2-{2-[3-(trans-4-methyl-cyclohexyl)-3-(4-phenyl-butyl)-ureido]-thiazol-5-ylsulfanyl}-propionic acid using 3-butyn-1-ol and (2-amino-thiazol-5-ylsulfanyl)-propionic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08362049B2
Source datasetuspto-grants-2013_01
ORD IDord-39c6d175a42f40bc98d9aeea8d598b4a
Source noteuspto-grants-2013_01