2-Methoxyethylamine → {6-Methoxy-2'-[(2-methoxy-ethylamino)-methyl]-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl ester

HRID 1810236Notes

Reaction equation

HRID 1810236 reaction equation
[CH3:1][O:2][C:3](=[O:25])[CH2:4][C:5]1[CH:6]=[C:7]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:22])([F:21])[F:20])=[CH:15][C:14]=2[CH:23]=O)[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1.[CH3:26][O:27][CH2:28][CH2:29][NH2:30]>>[CH3:1][O:2][C:3](=[O:25])[CH2:4][C:5]1[CH:6]=[C:7]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:21])([F:22])[F:20])=[CH:15][C:14]=2[CH2:23][NH:30][CH2:29][CH2:28][O:27][CH3:26])[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 80182-MethoxyethylamineHCID 86633167(2'-Formyl-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester

Product 1

HCID 66608573{6-Methoxy-2'-[(2-methoxy-ethylamino)-methyl]-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl ester

Procedure

Prepared according to the procedure described in Example 1, Step 5, using the following starting materials: (2′-formyl-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester and 2-methoxyethylamine.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-e50c93025ece4ea190947a32fd48ce5b
Source dataset
uspto-grants-2013_01
Patent number
US08362044B2

Reaction notes

Loading…