Pyrazole → HCID 66608050, compound

HRID 1810399Notes

Reaction equation

HRID 1810399 reaction equation
[CH2:1]([O:3][C:4](=[O:32])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:15]=2[CH2:24][N:25]([C:28](=[O:31])[CH2:29]Cl)[CH2:26][CH3:27])[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2].[NH:33]1[CH:37]=[CH:36][CH:35]=[N:34]1>>[CH2:1]([O:3][C:4](=[O:32])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:15]=2[CH2:24][N:25]([CH2:26][CH3:27])[C:28](=[O:31])[CH2:29][N:33]2[CH:37]=[CH:36][CH:35]=[N:34]2)[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2]

Participants

3

Reactant 2

HCID 1048PyrazoleHCID 66607317HCID 66607317, compound

Product 1

HCID 66608050HCID 66608050, compound

Procedure

Prepared according to the procedure described in Example 37, Step 2, using the following starting materials: (2′-{[(2-chloro-acetyl)-ethyl-amino]-methyl}-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester and pyrazole.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-6b64f6db25b84a87a4b48840f74df1f7
Source dataset
uspto-grants-2013_01
Patent number
US08362044B2

Reaction notes

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