HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66606831, compound → HCID 66607287, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66606831 | HCID 66606831 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 66607287 | HCID 66607287 | — |
Reaction Steps
To a solution of 2-{2′-[(benzyloxycarbonyl-ethyl-amino)-methyl]-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl}-propionic acid ethyl ester (0.11 mmol) in EtOH (12 mL) was added 10% palladium on carbon (0.050 g), and the reaction was stirred under a balloon of H2 at room temperature for 1 hour. The mixture was filtered through a pad of Celite and rinsed with EtOH. The filtrate was concentrated to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08362044B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-36fd1493b5d44dcdb809396b02f207dc |
| Source note | uspto-grants-2013_01 |