Hydrochloric Acid → 4-[3-{5-[4-(2-Methoxycarbonyl-acetyl)-piperazin-1-ylmethyl]-thiazol-2-yl}-1-(4-methyl cyclohexyl)-ureido]-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([C:15](=[O:16])[NH:17][c:18]2[s:19][c:20]([CH:23]=[O:24])[cH:21][n:22]2)[CH:25]2[CH2:26][CH2:27][CH:28]([CH3:31])[CH2:29][CH2:30]2)[CH2:12][CH2:13]1.[C:46]([O:47][BH-:48]([O:49][C:50](=[O:51])[CH3:52])[O:53][C:54](=[O:55])[CH3:56])(=[O:57])[CH3:58].[CH3:33][O:34][C:35]([CH2:36][C:37]([N:38]1[CH2:39][CH2:40][NH:41][CH2:42][CH2:43]1)=[O:44])=[O:45].[ClH:32].[Na+:59]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([C:15](=[O:16])[NH:17][c:18]2[s:19][c:20]([CH2:23][N:41]3[CH2:40][CH2:39][N:38]([C:37]([CH2:36][C:35]([O:34][CH3:33])=[O:45])=[O:44])[CH2:43][CH2:42]3)[cH:21][n:22]2)[CH:25]2[CH2:26][CH2:27][CH:28]([CH3:31])[CH2:29][CH2:30]2)[CH2:12][CH2:13]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-549f870e19884346afe1225301058a3c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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