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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1810489Generated: October 31, 2026

3,5-Difluorobenzyl Chloroformate → (2'-{[(3,5-Difluoro-benzyloxycarbonyl)-ethyl-amino]-methyl}-6'-methoxy-biphenyl-3-yl)-acetic acid methyl ester

https://huagongshe.com/reaction/1810489

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorobenzyl ChloroformateHCID 57458802—
Reactant(2'-Ethylaminomethyl-6'-methoxy-biphenyl-3-yl)-acetic acid methyl esterHCID 58149181—
Product(2'-{[(3,5-Difluoro-benzyloxycarbonyl)-ethyl-amino]-methyl}-6'-methoxy-biphenyl-3-yl)-acetic acid methyl esterHCID 58148900—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (2′-ethylaminomethyl-6′-methoxy-biphenyl-3-yl)-acetic acid methyl ester and 3,5-difluorobenzyl chloroformate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08362044B2
Source datasetuspto-grants-2013_01
ORD IDord-4512f0230d444904a97f583cab102410
Source noteuspto-grants-2013_01