2-Morpholinoethylamine → (6'-Methoxy-2'-[(2-morpholin-4-yl-ethylamino)-methyl]-biphenyl-3-yl}-acetic acid methyl ester

HRID 1810490Notes

Reaction equation

HRID 1810490 reaction equation
[CH3:1][O:2][C:3](=[O:21])[CH2:4][C:5]1[CH:6]=[C:7]([C:11]2[C:16]([O:17][CH3:18])=[CH:15][CH:14]=[CH:13][C:12]=2[CH:19]=O)[CH:8]=[CH:9][CH:10]=1.[NH2:22][CH2:23][CH2:24][N:25]1[CH2:30][CH2:29][O:28][CH2:27][CH2:26]1>>[CH3:1][O:2][C:3](=[O:21])[CH2:4][C:5]1[CH:6]=[C:7]([C:11]2[C:16]([O:17][CH3:18])=[CH:15][CH:14]=[CH:13][C:12]=2[CH2:19][NH:22][CH2:23][CH2:24][N:25]2[CH2:30][CH2:29][O:28][CH2:27][CH2:26]2)[CH:8]=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 4082852-MorpholinoethylamineHCID 58149056HCID 58149056, compound

Product 1

HCID 58148817(6'-Methoxy-2'-[(2-morpholin-4-yl-ethylamino)-methyl]-biphenyl-3-yl}-acetic acid methyl ester

Procedure

Prepared according to the procedure described in Example 33, Step 4, using the following starting materials: (2′-formyl-6′-methoxy-biphenyl-3-yl)-acetic acid methyl ester and 4-(2-aminoethyl)morpholine.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-a8b640765d5940bf889db9e664ad159d
Source dataset
uspto-grants-2013_01
Patent number
US08362044B2

Reaction notes

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