HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 2-(5-Bromo-2-fluorophenyl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 2-(5-Bromo-2-fluorophenyl)acetonitrile | HCID 23509631 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-(5-Bromo-2-fluorophenyl)acetic acid | HCID 3584690 | — |
Reaction Steps
(5-Bromo-2-fluoro-phenyl)-acetonitrile (0.5 g, 2.3 mmol) was treated with acetic acid (2 mL) and sulfuric acid (2 mL) in H2O (2 mL) at 95° C. for 5 hours. Aqueous worked-up afforded the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08362044B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-726ef524f4d445c29d58ec6b01609026 |
| Source note | uspto-grants-2013_01 |