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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1810556Generated: October 31, 2026

HCID 66607775, compound → HCID 66607438, compound

https://huagongshe.com/reaction/1810556

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66607775HCID 66607775—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 66607438HCID 66607438—

Reaction Steps

A solution of {2′-[(benzyloxycarbonyl-ethyl-amino)-methyl]-5-fluoro-4′-trifluoromethyl-biphenyl-3-yl}-acetic acid (0.025 g, 0.05 mmol) and 10% palladium on carbon (catalytic) in MeOH was hydrogenated under a balloon of H2 at room temperature for 2 hours. The mixture was filtered through a pad of Celite, and the filtrate was concentrated to give the title compound. M+H is 382.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08362044B2
Source datasetuspto-grants-2013_01
ORD IDord-16e1decc59e44f9f97f38af5581098b5
Source noteuspto-grants-2013_01