Cyclopropanecarbonyl chloride → HCID 66606761, compound

HRID 1810592Notes

Reaction equation

HRID 1810592 reaction equation
[CH2:1]([NH:3][CH2:4][C:5]1[CH:10]=[C:9]([C:11]([F:14])([F:13])[F:12])[CH:8]=[CH:7][C:6]=1[C:15]1[C:20]([O:21][CH3:22])=[CH:19][CH:18]=[C:17]([CH2:23][C:24]#[N:25])[CH:16]=1)[CH3:2].[CH:26]1([C:29](Cl)=[O:30])[CH2:28][CH2:27]1>>[C:24]([CH2:23][C:17]1[CH:18]=[CH:19][C:20]([O:21][CH3:22])=[C:15]([C:6]2[CH:7]=[CH:8][C:9]([C:11]([F:12])([F:13])[F:14])=[CH:10][C:5]=2[CH2:4][N:3]([CH2:1][CH3:2])[C:29]([CH:26]2[CH2:28][CH2:27]2)=[O:30])[CH:16]=1)#[N:25]

Participants

3

Reactant 2

HCID 77637Cyclopropanecarbonyl chlorideHCID 66606246HCID 66606246, compound

Product 1

HCID 66606761HCID 66606761, compound

Procedure

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (2′-ethylaminomethyl-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-acetonitrile and cyclopropanecarbonyl chloride. M+H is 417.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-c366420d90794cd595a79ee1c91cff31
Source dataset
uspto-grants-2013_01
Patent number
US08362044B2

Reaction notes

Loading…