HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57516332, compound → 2-(2,2,2-Trifluoroethoxy)pyridin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57516332 | HCID 57516332 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(2,2,2-Trifluoroethoxy)pyridin-4-amine | HCID 57516331 | 100% |
Reaction Steps
4-Nitro-2-(2,2,2-trifluoro-ethoxy)-pyridine (1.11 g, 5 mmol) in 40 mL EtOH and 50 mg 10% Pd/C is placed under hydrogen atmosphere at room temp for 16 h. The solvent is removed under reduced pressure to give 0.9 g, 100% yield of 2-(2,2,2-trifluoro-ethoxy)-pyridin-4-ylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08362249B2 |
| Source dataset | uspto-grants-2013_01 |
| ORD ID | ord-9ea68daaa8b24573a0ed4a1d85d44ed6 |
| Source note | uspto-grants-2013_01 |