反应详情

温度

77.5 °C

Added 3.8 Kgs. of hydrochloric acid to a solution of 100 Kgs. of 2-acetyl thiophene, 81.5 Kgs. of dimethylamine hydrochloride, 35.4 Kgs. parafomaldehyde and 250 liters of isopropyl alcohol. Heated the reaction mixture to 75-80° C. Stirred the reaction mixture for 6 hours at 75-80° C. Cooled the reaction mixture to 0-5C. Stirred the reaction mixture for 2 hours at 0-5° C. Filtered the solid and washed with isopropyl alcohol.

1. additionAdded 3.8 Kgs
2. temperatureCooled the reaction mixture to 0-5C
3. stirringStirred the reaction mixture for 2 hours at 0-5° C
4. filtrationFiltered the solid
5. washwashed with isopropyl alcohol