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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 181190Generated: October 30, 2026

Dimethylformamide → 2,4-Diamino-6-methyl-5-[3-(4-trifluoromethylphenyl)-3-methyl-1-butynyl]pyrimidine

https://huagongshe.com/reaction/181190

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantPiperidineHCID 8082—
ReactantCopper iodideHCID 83717—
Reactant1-(2-Methylbut-3-yn-2-yl)-4-(trifluoromethyl)benzeneHCID 15332573—
Reactant5-Iodo-6-methylpyrimidine-2,4-diamineHCID 15855792—
Product2,4-Diamino-6-methyl-5-[3-(4-trifluoromethylphenyl)-3-methyl-1-butynyl]pyrimidineHCID 21467974—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-6bbc3d1ab28548fc9cf586405b5fd0a3
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)