Dimethylformamide → 2,4-Diamino-6-methyl-5-[3-(4-trifluoromethylphenyl)-3-methyl-1-butynyl]pyrimidine
Reaction equation
[CH2:26]1[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]1.[CH3:11][C:12]([C:13]#[CH:14])([CH3:15])[c:16]1[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]1.[CH3:32][N:33]([CH3:34])[CH:35]=[O:36].[Cu:37]([I:38])[I:39].[NH2:1][c:2]1[n:3][c:4]([CH3:10])[c:5]([I:9])[c:6]([NH2:8])[n:7]1>>[NH2:1][c:2]1[n:3][c:4]([CH3:10])[c:5]([C:14]#[C:13][C:12]([CH3:11])([CH3:15])[c:16]2[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]2)[c:6]([NH2:8])[n:7]1Participants
6
Sources & evidence
- ORD record
- ord-6bbc3d1ab28548fc9cf586405b5fd0a3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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