HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22505093, compound → HCID 22505002, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22505093 | HCID 22505093 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 22505002 | HCID 22505002 | — |
Reaction Steps
10% Palladium on carbon (0.02 g) was added to 3-(2,6-difluoro-4-nitro-phenyl)-6-oxa-3-aza-bicyclo[3.1.0]hexane (0.2 g, 0.83 mmol) dissolved in ethyl acetate (8.0 mL). The flask was charged with hydrogen gas and the mixture was stirred at room temperature for 3 h. The reaction mixture was filtered through celite and the solvent removed to get the title compound which was used directly in the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06875784B2 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-a86c43f291124a21a6ab0c32345eab09 |
| Source note | uspto-grants-2005_04 |