Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1814037Generated: November 1, 2026

HCID 22505093, compound → HCID 22505002, compound

https://huagongshe.com/reaction/1814037

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22505093HCID 22505093—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthyl AcetateHCID 8857—
ProductHCID 22505002HCID 22505002—

Reaction Steps

10% Palladium on carbon (0.02 g) was added to 3-(2,6-difluoro-4-nitro-phenyl)-6-oxa-3-aza-bicyclo[3.1.0]hexane (0.2 g, 0.83 mmol) dissolved in ethyl acetate (8.0 mL). The flask was charged with hydrogen gas and the mixture was stirred at room temperature for 3 h. The reaction mixture was filtered through celite and the solvent removed to get the title compound which was used directly in the next reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06875784B2
Source datasetuspto-grants-2005_04
ORD IDord-a86c43f291124a21a6ab0c32345eab09
Source noteuspto-grants-2005_04