HuagongsheHuagongshe Chemistry Print Report · For research reference only
{6-[4-(5-Trifluoromethyl-pyridin-2-yl)-benzylsulfanyl]-chroman-2-yl}-acetic acid ethyl ester → {6-[4-(5-Trifluoromethyl-pyridin-2-yl)-benzylsulfanyl]-chroman-2-yl}-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | {6-[4-(5-Trifluoromethyl-pyridin-2-yl)-benzylsulfanyl]-chroman-2-yl}-acetic acid ethyl ester | HCID 20770775 | — |
| Reactant | {4-[5-(Trifluoromethyl)pyridin-2-yl]phenyl}methanol | HCID 22280022 | — |
| Product | {6-[4-(5-Trifluoromethyl-pyridin-2-yl)-benzylsulfanyl]-chroman-2-yl}-acetic acid | HCID 11155377 | — |
Reaction Steps
The title compound was prepared in the manner analogous to example 5E using 10D. MS m/z 272 (M+1). Step 6. Preparation of {6-[4-(5-Trifluoromethyl-pyridin-2-yl)-benzylsulfanyl]-chroman-2-yl}-acetic acid ethyl ester (Compound 10F)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06875780B2 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-f1abd0279b4948c8810285abc56fa88f |
| Source note | uspto-grants-2005_04 |