HuagongsheHuagongshe Chemistry Print Report · For research reference only
{5-[4-(Trifluoromethyl)phenyl]isoxazol-3-yl}methan-1-ol → {6-[5-(4-Trifluoromethyl-phenyl)-isoxazol-3-ylmethylsulfanyl]-chroman-2-yl}-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | {5-[4-(Trifluoromethyl)phenyl]isoxazol-3-yl}methan-1-ol | HCID 22064161 | — |
| Reactant | {6-[5-(4-Trifluoromethyl-phenyl)-isoxazol-3-ylmethylsulfanyl]-chroman-2-yl}-acetic acid ethyl ester | HCID 69514714 | — |
| Product | {6-[5-(4-Trifluoromethyl-phenyl)-isoxazol-3-ylmethylsulfanyl]-chroman-2-yl}-acetic acid | HCID 11396735 | — |
Reaction Steps
The title compound was prepared in a manner analogous to Example 5E using 13B. MS m/z 262 (M+1). Step 4. Preparation of {6-[5-(4-Trifluoromethyl-phenyl)-isoxazol-3-ylmethylsulfanyl]-chroman-2-yl}-acetic acid ethyl ester (Compound 13D)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06875780B2 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-ebadb0914d2b487f814d10cc48f62f63 |
| Source note | uspto-grants-2005_04 |