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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1814182Generated: November 2, 2026

3-(Chloromethyl)-5-(4-chlorophenyl)-1,2-oxazole → 2-(6-((5-(4-Chlorophenyl)isoxazol-3-yl)methoxy)-5-methylbenzo[b]thiophen-3-yl)acetic acid

https://huagongshe.com/reaction/1814182

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Chloromethyl)-5-(4-chlorophenyl)-1,2-oxazoleHCID 1481100—
Reactant(6-Hydroxy-5-methyl-benzo[b]thiophen-3-yl)-acetic acid methyl esterHCID 20770860—
Reactant{7-[5-(4-Chloro-phenyl)-isoxazol-3-ylmethoxy]-benzo[b]thiophen-3-yl}-acetic acid methyl esterHCID 20770869—
Product2-(6-((5-(4-Chlorophenyl)isoxazol-3-yl)methoxy)-5-methylbenzo[b]thiophen-3-yl)acetic acidHCID 22504843—

Reaction Steps

The title compound was prepared from commercially available 3-chloromethyl-5-(4-chloro-phenyl)-isoxazole and compound 78C in a manner analogous to compound 77C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06875780B2
Source datasetuspto-grants-2005_04
ORD IDord-8e312637b6d64f34b57a4821104b26f9
Source noteuspto-grants-2005_04