HuagongsheHuagongshe Chemistry Print Report · For research reference only
Serinol → 2-[[(3-Chloro-2-fluorophenyl)methyl]thio]-4-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-7(8H)-pteridinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Serinol | HCID 68294 | — |
| Reactant | 4-Bromo-2-[[(3-chloro-2-fluorophenyl)methyl]thio]-7(8H)-pteridinone | HCID 22505983 | — |
| Product | 2-[[(3-Chloro-2-fluorophenyl)methyl]thio]-4-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-7(8H)-pteridinone | HCID 22505942 | 66.3% |
Reaction Steps
The titled compound (51 mg) was prepared by the method of Example 6, step (f) using the product from Example 6, step (e) (75 mg) and 2-amino-1,3-propanediol (37 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06875868B2 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-313557b7d540455abf68f3582d8b2d38 |
| Source note | uspto-grants-2005_04 |