HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Methylphenyl)methanethiol → 4-[[(1R)-2-Hydroxy-1-methylethyl]amino]-2-[[(3-methylphenyl)methyl]thio]-7(8H)-pteridinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Methylphenyl)methanethiol | HCID 2801207 | — |
| Reactant | 2-[[(2,3-Difluorophenyl)methyl]sulfonyl]-4-[[(1R)-2-hydroxy-1-methylethyl]amino]-7(8H)-pteridinone | HCID 68817193 | — |
| Product | 4-[[(1R)-2-Hydroxy-1-methylethyl]amino]-2-[[(3-methylphenyl)methyl]thio]-7(8H)-pteridinone | HCID 68814142 | 43.2% |
Reaction Steps
The titled compound (75 mg) was prepared by the method of Example 13, step (c) using the product from Example 13, step (a) (0.20 g) and 3-methyl-benzenemethanethiol (75 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06875868B2 |
| Source dataset | uspto-grants-2005_04 |
| ORD ID | ord-6c5ce1bad0044461bdbe19dd603570a1 |
| Source note | uspto-grants-2005_04 |