Methanol → N-(4-Chloro-2-(hydroxymethyl)-5-(4-(3-(2-methoxyphenyl)-5-methylisoxazole-4-carbonyl)piperazin-1-yl)phenyl)-4-(dimethylamino)benzamide
Reaction equation
[BH4-:46].[CH2:50]1[O:51][CH2:52][CH2:53][CH2:54]1.[CH3:48][OH:49].[Cl:1][c:2]1[c:3]([N:24]2[CH2:25][CH2:26][N:27]([C:30](=[O:31])[c:32]3[c:33](-[c:38]4[c:39]([O:44][CH3:45])[cH:40][cH:41][cH:42][cH:43]4)[n:34][o:35][c:36]3[CH3:37])[CH2:28][CH2:29]2)[cH:4][c:5]([NH:12][C:13]([c:14]2[cH:15][cH:16][c:17]([N:20]([CH3:21])[CH3:22])[cH:18][cH:19]2)=[O:23])[c:6]([C:7](=[O:8])[O:9][CH3:10])[cH:11]1.[Na+:47]>>[Cl:1][c:2]1[c:3]([N:24]2[CH2:25][CH2:26][N:27]([C:30](=[O:31])[c:32]3[c:33](-[c:38]4[c:39]([O:44][CH3:45])[cH:40][cH:41][cH:42][cH:43]4)[n:34][o:35][c:36]3[CH3:37])[CH2:28][CH2:29]2)[cH:4][c:5]([NH:12][C:13]([c:14]2[cH:15][cH:16][c:17]([N:20]([CH3:21])[CH3:22])[cH:18][cH:19]2)=[O:23])[c:6]([CH2:7][OH:8])[cH:11]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f933c6f424f94162a8d153dd48886c4b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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